MILAN, ITALY, Sep 27, 2011 (MARKETWIRE via COMTEX) — MolMed S.p.A. (milan:MLM) presented new data from four clinical trials on its investigational anticancer drug NGR-hTNF at the European Multidisciplinary Cancer Congress, taking place in Stockholm on 23-27 September 2011. The Company reported updated interim results from a randomised Phase II trial in non-small-cell lung cancer, and follow-up data from two completed Phase II trials in recurrent ovarian cancer and relapsed small-cell lung cancer. The clinical development update also included results from a Phase I trial at high doses.

Claudio Bordignon, chairman and CEO of MolMed, comments: “The new interim randomised data in lung cancer look promising particularly in patients with the squamous cell histological subtype, a severe form of lung cancer with high need of new treatment options. As to new follow-up data from the two completed trials, the long-term clinical benefit in two poor-prognosis tumours such as relapsed ovarian and small-cell lung cancer, observed in patients presenting normal lymphocyte counts, confirms the dual mode by which NGR-hTNF exerts its effect, destroying the tumour vasculature and exploiting the effectors of the immune system. There is a growing need for tools, among which predictive biomarkers, to identify patients responding to a specific drug: for NGR-hTNF, a simple blood test such as lymphocyte counts correlates with clinical benefit. This parameter, together with others, might contribute in the future to the identification of patients more likely to get prolonged therapeutic benefit.”