A previously unknown effect of an infectious agent relevant to the prevention and/or treatment of lung cancer has been discovered by a UMDNJ research team led by Melissa Rogers, Ph.D., professor of Biochemistry and Molecular Biology at UMDNJ-New Jersey Medical School.

The infectious agent, mycoplasma bacterium, induces the synthesis of an important growth factor, BMP2, in lung cells. After enough time, mycoplasma can convert normal lung cells into cells that form tumors. BMP2 may accelerate this process. With the help of a two-year grant for $120,000 from the New Jersey Commission on Cancer Research and a Team Science Initiative Grant from UMDNJ, Dr. Rogers and her collaborator, Dr. John Langenfeld of UMDNJ-Robert Wood Johnson Medical School, are working to understand the relationship between bacterial infection and BMP2 in lung tumors.